Mixing CBD with Prednisone: A Guide

cbd and prednisone

Updated Date: February 23rd 2023

Cannabidiol (CBD) is a compound found in the cannabis plant that is believed to have potential therapeutic benefits. 

On the other hand, prednisone is a steroid used to treat inflammatory conditions and suppress immune system activity. 

With both increasingly popular treatments on the rise, you may wonder if mixing CBD with prednisone is safe. 

Read on for our guide to mixing CBD with prednisone so you can make an informed decision about your treatment options.

Can You Mix CBD and Prednisone?

The short answer is yes, you can safely mix CBD and prednisone. 

However, before deciding to combine the two, it’s essential to understand the potential risks and benefits of both treatments.

Potential Benefits of Mixing CBD and Prednisone

CBD has been studied for its potential therapeutic uses, including reducing inflammation, pain relief, easing anxiety, and improving sleep. 

Some studies suggest combining CBD with prednisone could provide an even more significant benefit than taking either treatment alone.

In addition, some people find that combining CBD with prednisone helps reduce side effects like insomnia or headaches commonly associated with taking prednisone alone. 

However, more research is needed to fully understand the effects of combining these two treatments.

Potential Risks of Mixing CBD and Prednisone

When taken together, CBD and prednisone can increase the risk of specific side effects. For example, combining the two may worsen fatigue or cause sleep disturbances. 

It’s also important to note that CBD can interact with other medications, so it's always best to speak with your doctor before taking any new treatments.

Additionally, it’s essential to understand the potential for drug interactions when mixing CBD and prednisone. 

These drugs can interact in unpredictable ways, so you must talk to your doctor about any medications you are currently taking before starting a new treatment plan that includes CBD and prednisone.

Things To Consider Before Mixing CBD With Prednisone

When deciding whether or not to mix CBD with prednisone, it’s essential to consider any potential risks and benefits. 

Speak with your doctor about the possible interactions between CBD, prednisone, and other medications you currently take.

It’s also important to do your research before mixing CBD with prednisone. 

Make sure to read up on all the available studies and research into both treatments to make an informed decision about your treatment plan.


Mixing CBD with prednisone is a personal decision that should be made with careful consideration of potential risks and benefits. 

Always talk to your doctor before starting a new treatment plan, and do your research to make an informed decision.

Read the available studies and research for more information on CBD and prednisone. 

You can also speak with your doctor to learn about any potential risks or benefits of combining these two treatments.

If you have Lupus and looking for a good CBD product, check out our article - it’s called best CBD oil for lupus.

Written by Jenny Martin, CBD Journalist

Medically Reviewed by Kimberly Langdon, MD